Corpus: Supraoptic nucleus
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English:
Definition[Bearbeiten]
The nucleus supraopticus is an important nucleus of the hypothalamus. It lies above the optic tract and is part of the neuroendocrine system of the posterior lobe of the pituitary gland.
Neurophysiology[Bearbeiten]
In the perikarya of the supraoptic nucleus, the hormones ADH and small amounts of oxytocin are produced together with their respective neurophysins. They reach the neurohypophysis via axoplasmic transport, where they are stored and, if necessary, proteolytically cleaved and released into the bloodstream.
Clinic[Bearbeiten]
Damage to the nucleus or the posterior lobe of the pituitary gland leads to the clinical picture of central diabetes insipidus.