Corpus: Parahippocampal gyrus

The parahippocampal gyrus is a region of the cerebral cortex that surrounds the hippocampus and consists of grey matter. It plays an important role in memory.

The parahippocampal gyrus is part of the outer arc of the limbic system. It has a six-layered cortex and is located in the medial areas of the temporal lobe. Together with the medial part of the fusiform gyrus, its posterior part forms the so-called parahippocampal cortex. In the rostral part of the parahippocampal gyrus there is a subregion that is important for recognising landscape scenes, the "parahippocampal place area" (PPA). Anteriorly, the parahippocampal gyrus runs into the uncus.

Hippocampal sclerosis (mesial temporal sclerosis) is a frequent neuropathological finding in the context of therapy-refractory temporal lobe epilepsy.