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Difference between revisions of "HOMA"

 
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* [http://www.dtu.ox.ac.uk/index.php?maindoc=/homa/ HOMA Calculator], an application for calculating HOMA on Mac and Windows
 
* [http://www.dtu.ox.ac.uk/index.php?maindoc=/homa/ HOMA Calculator], an application for calculating HOMA on Mac and Windows
  
== Literatur ==
+
== References ==
 
*Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. ''Diabetologia''. 1985 Jul;28(7):412
 
*Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. ''Diabetologia''. 1985 Jul;28(7):412
 
*Mehmet Keskin, Selim Kurtoglu, Mustafa Kendirci, M. Emre Atabek und Cevat Yazici. [http://pediatrics.aappublications.org/cgi/content/abstract/115/4/e500 Homeostasis Model Assessment Is More Reliable Than the Fasting Glucose/Insulin Ratio and Quantitative Insulin Sensitivity Check Index for Assessing Insulin Resistance Among Obese Children and Adolescents]. Pediatrics 115 No. 4 April 2005, pp. e500-e503 (doi:10.1542/peds.2004-1921)
 
*Mehmet Keskin, Selim Kurtoglu, Mustafa Kendirci, M. Emre Atabek und Cevat Yazici. [http://pediatrics.aappublications.org/cgi/content/abstract/115/4/e500 Homeostasis Model Assessment Is More Reliable Than the Fasting Glucose/Insulin Ratio and Quantitative Insulin Sensitivity Check Index for Assessing Insulin Resistance Among Obese Children and Adolescents]. Pediatrics 115 No. 4 April 2005, pp. e500-e503 (doi:10.1542/peds.2004-1921)
 
*Yiqing Song, JoAnn E. Manson, Lesley Tinker, Barbara V. Howard, Lewis H. Kuller, Lauren Nathan, Nader Rifai und Simin Liu. [http://care.diabetesjournals.org/cgi/content/full/30/7/1747 Insulin Sensitivity and Insulin Secretion Determined by Homeostasis Model Assessment and Risk of Diabetes in a Multiethnic Cohort of Women]. Diabetes Care 30:1747-1752, 2007 (doi: 10.2337/dc07-0358)
 
*Yiqing Song, JoAnn E. Manson, Lesley Tinker, Barbara V. Howard, Lewis H. Kuller, Lauren Nathan, Nader Rifai und Simin Liu. [http://care.diabetesjournals.org/cgi/content/full/30/7/1747 Insulin Sensitivity and Insulin Secretion Determined by Homeostasis Model Assessment and Risk of Diabetes in a Multiethnic Cohort of Women]. Diabetes Care 30:1747-1752, 2007 (doi: 10.2337/dc07-0358)

Latest revision as of 17:53, 12 June 2009

Homeostasis model assessment (HOMA) is a diagnostical procedure that is based on the homeostasis model of carbohydrate metabolism.

1 Physiological foundation

The HOMA approach is grounded in the homeostasis model of Turner et al., a mathematical model of feedback coupled interaction of insulin and glucose in carbohydrate homeostasis.

2 Calculation

In HOMA, simultaneously determined glucose and insulin levels in fasting state are entered in equations that calculate beta cell function and insulin sensitivity.

  • HOMA Beta = 20 * fasting insulin (mU/l) / (fasting glucose (mmol/l) - 3,5)
  • HOMA IR = fasting insulin (mU/l) * fasting glucose (mmol/l) / 22,5

3 See also

Alternative approaches are:

4 Weblinks

5 References

This page was last edited on 12 June 2009, at 17:53.

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