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Difference between revisions of "Diabetes mellitus"

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==Definition==
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'''Diabetes mellitus''' (DM) is a severe metabolic disease that is characterized by persistent high [[blood sugar]] levels ([[hyperglycemia]]) and numerous accompanying symptoms.
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==Classification==
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According to the [[American Diabetes Association]] Diabetes mellitus is classified as follows:
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* 1: [[Insulin]] deficiency
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** 1A: [[Insulin]] deficieny (autoimmune origin)
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** 1B: [[Insulin]] deficiency (idiopathic)
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* 2: Hybrid of secretory dysfunction and [[Insulin]] resistance
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** DM 2 with leading secretory dysfunction
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** DM 2 with leading insulin resistance
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*3: Secondary and genetical forms of DM
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** 3A: Genetical disorder of pancreatic [[Beta cell]]s
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** 3B: Genetically mediated [[Insulin]] resistance
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** 3C: Pancreoprivic Diabetes mellitus
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** 3D: Secondary endocrine Diabetes mellitus
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** 3E: DM mediated by chemical agents or drugs
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** 3F: DM mediated by infectious agents
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** 3G: Immunologically caused DM
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** 3H: Other genetic syndromes
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*4: [[Gestation]]al DM
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==Prognosis==
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Prognosis of Diabetes mellitus depends from an optimal metabolic control, as shown by large clinical studies like [[DCCC]]. Patients under continued [[hyperglycemia|hyperglycemic]] conditions are prone to high risk for developing complications like [[diabetic angiopathy]], [[diabetic neuropathy|neuropathy]], [[diabetic retinopathy|retinopathy]] or [[diabetic nephropathy|nephropathy]]. ON the other hand, [[hypoglycemia]] bears high acute threats.
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==Therapy==
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Therapy of Diabetes mellitus is different for different diabetes types. DM with insulin deficiency requires substitution of [[insulin]]. Other therapeutic options are modulation of insulin resistance and lifestyle modifying interventions.
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Revision as of 18:06, 24 October 2006

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