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Homeostasis model assessment (HOMA) is a diagnostical procedure that is based on the homeostasis model of carbohydrate metabolism.

1 Physiological foundation

The HOMA approach is grounded in the homeostasis model of Turner et al., a mathematical model of feedback coupled interaction of insulin and glucose in carbohydrate homeostasis.

2 Calculation

In HOMA, simultaneously determined glucose and insulin levels in fasting state are entered in equations that calculate beta cell function and insulin sensitivity.

  • HOMA Beta = 20 * fasting insulin (mU/l) / (fasting glucose (mmol/l) - 3,5)
  • HOMA IR = fasting insulin (mU/l) * fasting glucose (mmol/l) / 22,5

3 See also

Alternative approaches are:

4 Weblinks

5 References

This page was last edited on 12 June 2009, at 18:53.

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