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Vitamin B6

Synonym: pyridoxine

1 Definition

Vitamin B6 is a collective term for pyridoxine, pyridoxal and pyridoxamine. These three precursors of pyridoxal phosphate (PLP), which is the active form of vitamin B6, are interconvertible. The human body is not able to produce pyridoxal phosphate by its own. Hence, an uptake by nutrition is required.

2 Structure

3 Biochemical role

PLP function as a coenzyme in the following reactions:

3.1 Amino acid dependent reactions

3.2 Other reactions

4 Requirement

The requirement of vitamin B6 is protein dependent. People require about 0.02 mg/g proteins. For men an uptake of about 1.8 mg/day and for women about 1.6 mg/day is recommended.

5 Deficiency

Very rare in human beings.

Symptoms of vitamin B6 deficiency:

  • Anemia due to the dependence of heme biosynthesis
  • neurological symptoms are often observed

6 References

Tiberiu Nistor - Basic in descriptive biochemistry

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Specialties: Biology

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