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Peripheral arterial disease

Synonyms: PAD, PAOD, peripheral arterial occlusive disease, intermittent claudication
German: Periphere arterielle Verschlusskrankheit

1 Definition

The term peripheral arterial disease (PAD) describes a symptom complex that develops due to a progressive stenosis or the occlusion of the arterial vessels of the arm, or - more often - of the leg.

see also: intermittent claudication

2 Pathogenesis

PAD develops on the basis of an arteriosclerosis in 90% of the cases.

3 Epidemiology

Peripheral arterial disease is a relatively common disease. Prevalence is stated at 10% of the population over 50 years of age in Germany. However, the disease becomes symptomatic in only one third of the cases. Men are affected around four times as much as women.

4 Classification

4.1 ...according to symptoms

PAD of the vessels of the leg is divided as per sypmtoms according to Fontaine into:

Stage   Symptoms
Stage I   no symptoms, mostly an accidental finding (eg. missing peripheral pulses)
Stage II   intermittent claudication
  IIa claudication when walking a distance > 200m
  IIb claudication when walking a distance < 200m
Stage III   Rest pain
Stage IV   Trophic disorders (necrosis, ulcers, gangrene)

4.2 ...according to localization

  • One-level-disease
  • Multilevel-disease

4.3 ...according to disease progression

5 Diagnostics

6 Therapy

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