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Agonist

German: Agonist

1 Definition

Agonist means "contestant". It refers to a substance or structure that is regarding to a specific action the causative agent, for instance a muscle that mediates a specific movement.

The opposite of an agonist is an antagonist.

2 Pharmacology

In pharmacology, an agonist refers to molecule that is able to bind to a cellular receptor to produce a biological response. Generally, agonists take on the role of an endogenous substance.

see also: superagonist

3 Neurobiology

A substance that mimics the action of a neurotransmitter by binding to its specific receptor and thereby causes equivalent effects. The principle of agonism is used in drugs that are used as substitutes when there is shortage in a body’s own transmitter (e.g. L-DOPA in dopamine deficiency).

4 Anatomy

Muscle that mediates a specific movement (e.g. flexion or extension) that is opposed by a muscle that works as an antagonist (antagonistic pairs).

Specialties: Anatomy

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